Pseudocyesis: A complication of antipsychotic-induced increased prolactin levels and weight gain

Increased body weight associated with prolactin secreting pituitary adenomas: weight loss with normalization of prolactin levels.

OBJECTIVE Hyperprolactinaemia in humans may be associated with a high prevalence of obesity but the nature of this link is poorly defined. The aim of this study was to establish the relationship between hyperprolactinaemia and body weight in patients with prolactin-secreting pituitary tumours. DESIGN We conducted a retrospective study of prolactinoma patients treated at the Endocrine Institut...

Metformin in prevention and treatment of antipsychotic induced weight gain: a systematic review and meta-analysis

BACKGROUND Most antipsychotics are associated with weight gain and other metabolic complications. Several randomized trials have shown metformin to be effective, but this still hasn't been included in clinical guidelines on managing antipsychotic induced weight gain. METHODS All double blind placebo controlled trials assessing the efficacy of metformin in the treatment of antipsychotic induce...

Reversal of antipsychotic-induced hyperprolactinemia, weight gain, and dyslipidemia by aripiprazole: A case report.

A comprehensive analysis of mitochondrial genes variants and their association with antipsychotic-induced weight gain.

Antipsychotic Induced Weight Gain (AIWG) is a common and severe side effect of many antipsychotic medications. Mitochondria play a vital role for whole-body energy homeostasis and there is increasing evidence that antipsychotics modulate mitochondrial function. This study aimed to examine the role of variants in nuclear-encoded mitochondrial genes and the mitochondrial DNA (mtDNA) in conferring...

Antipsychotic-induced weight gain in chronic and first-episode psychotic disorders: a systematic critical reappraisal.

Antipsychotic-induced weight gain is an important issue in the treatment of psychotic illnesses, and affects 80% of individuals being treated with antipsychotic drugs. However, the true dimension of weight gain and many accepted 'facts' in this area remain unclear as most research has been conducted in short-term trials and has included individuals receiving prolonged antipsychotic treatment. T...